Real Madrid will be without the services of Vinicius Junior and Karim Benzema for Saturday's La Liga contest with Sevilla at Estadio Ramon.
Vinicius has had his red card from the 1-0 loss at Valencia last weekend overturned, but he is currently suffering with knee inflammation and has not been named in the squad.
Los Blancos head coach Carlo Ancelotti will not be taking any chances when it comes to the Brazilian's fitness, so he misses out alongside Marco Asensio, who has a muscular issue.
Benzema, meanwhile, suffered a nasty cut on his foot during Wednesday's 2-1 win over Rayo Vallecano, with the striker needing stitches to close up the wound.
As a result, the Frenchman is out of this match, which could lead to Rodrygo operating through the middle and Eden Hazard being introduced into a wide area.
Mariano Diaz would have been another option, but the striker was absent against Rayo due to a muscular problem and remains out.
Ancelotti is expected to again shuffle his pack for this match, with Dani Ceballos and Aurelien Tchouameni potentially both coming into the midfield.
Eder Militao was an unused substitute last time out, meanwhile, so the Brazil international should also return to the starting side for the contest at Estadio Ramon, but Dani Carvajal is suspended following his yellow card against Rayo.
Real Madrid possible starting lineup: Courtois; Vazquez, Militao, Rudiger, Alaba; Camavinga, Tchouameni, Ceballos; Valverde, Rodrygo, Hazard body check tags ::
