Barcelona boss Xavi will be without a number of key players for his first game since he revealed his intention to leave in the summer, with his side set to face Osasuna in Wednesday's La Liga contest.

Joao Felix recently joined Barcelona's absentee list after the Atletico Madrid loanee suffered an ankle injury in Tuesday's training session

Felix is joined on the sidelines by Marc-Andre ter Stegen (back), Alejandro Balde (hamstring), Gavi (knee), Marcos Alonso (back), Sergi Roberto (Achilles) and Raphinha (thigh).

Inigo Martinez, who has missed the last six matches, is making progress in his injury recovery, but the defender is unlikely to be ready for Wednesday's contest.

After replacing Andreas Christensen at the break in Saturday's 5-3 defeat to Villarreal, 17-year-old Pau Cubarsi could come into the side to partner Ronald Araujo in central defence, with the pair set to offer protection to goalkeeper Inaki Pena.

Joao Cancelo came off the bench at the weekend to make his first appearance since recovering from a knee problem, and the Manchester City loanee is now expected to start at left-back, while Jules Kounde will retain his place on the opposite side of the back four.

Pedri is likely to be rewarded with a start after marking Saturday's substitute appearance with a goal, and the Spain international will be joined in the engine room by Frenkie de Jong and Ilkay Gundogan.

Xavi may present Lamine Yamal with a fourth consecutive start on the right wing, while Ferran Torres could replace Felix on the opposite flank.

Despite failing to score in his last five league games, Robert Lewandowski is poised to retain his spot in the centre of Barcelona's forward line.

Barcelona possible starting lineup: Pena; Kounde, Araujo, Cubarsi, Cancelo; Pedri, De Jong, Gundogan; Yamal, Torres, Lewandowski