Man Utd vs. Everton (Saturday, 12.30pm)
Fresh from Wednesday's last-gasp win over Villarreal in the Champions League, Manchester United will resume their Premier League campaign at home to Everton on Saturday afternoon.
Man United are currently fourth in the table, one point behind leaders Liverpool, while Rafael Benitez's Everton occupy fifth, level on points (13) with their opponents at Old Trafford this weekend.
We say: Manchester United 2-0 Everton
A full-strength Everton would have fancied their chances of picking up at least a point at Old Trafford, but the Toffees will be missing a number of important players. Man United will surely be better than they were against Villarreal on Wednesday, and we are expecting the Red Devils to collect all three points this weekend, potentially keeping a rare clean sheet in the process.
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> How Manchester United could line up against Everton
> Man United injury, suspension list vs. Everton
> Cristiano Ronaldo's record vs. Everton
Burnley vs. Norwich (Saturday, 3.00pm)
Two sides still searching for their first wins of the new Premier League season prepare for battle at Turf Moor on Saturday, as Burnley play host to Norwich City.
The Clarets claimed an impressive point in a 2-2 draw with Leicester City last time out, whereas Daniel Farke's side suffered a 2-0 defeat to Everton.
We say: Burnley 2-1 Norwich City
Burnley's dire home form and Norwich's away day struggles should make for an interesting encounter this weekend, with both sides viewing this fixture as their most winnable one of the Premier League season so far.
However, Burnley talisman Wood loves a goal against the Norwich, and their performance at Leicester did catch the eye, so we expect the hosts to be the ones to get off the mark at the seventh attempt while the Canaries' streak of losses continues.
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Chelsea vs. Southampton (Saturday, 3.00pm)
Seeking to avoid a third successive defeat in all competitions, Chelsea welcome winless Southampton to Stamford Bridge for Saturday afternoon's Premier League clash.
The Blues' most recent top-flight battle saw them lose 1-0 to champions Manchester City, while Ralph Hasenhuttl's side suffered defeat by the same scoreline to Wolverhampton Wanderers.
We say: Chelsea 2-0 Southampton
Southampton have enjoyed a string of positive results at Stamford Bridge over the past few seasons and will aim to take advantage of Chelsea's depleted confidence, but they are hardly high on morale themselves.
Tuchel's side will view this encounter as the ideal opportunity to get back on track before the international break, and we can only back the Blues to return to winning ways and leave Southampton still searching for their first three points of the new term.
> Click here to read our full preview for this match
> How Chelsea could line up against Southampton
> Chelsea injury, suspension list vs. Southampton
> Romelu Lukaku's record against Southampton
Leeds vs. Watford (Saturday, 3.00pm)
Leeds United's search for their first win of the 2021-22 Premier League season will continue on Saturday afternoon when they welcome Watford to Elland Road.
The Whites currently sit 18th in the table, having picked up just three points from six matches this term, while Watford have gathered seven points from their six fixtures to occupy 12th position.
We say: Leeds United 1-1 Watford
Leeds would have earmarked this match as the perfect chance to put three points on the board, but Watford have made an encouraging start to the season. We are expecting a very close match at Elland Road and have had to settle on a low-scoring draw, which would certainly be a better result for the visitors.
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Wolves vs. Newcastle (Saturday, 3.00pm)
Wolverhampton Wanderers will endeavour to make it back-to-back wins in the Premier League when they welcome Newcastle United to Molineux for Saturday's clash.
Bruno Lage's side marched to a 1-0 victory over Southampton in gameweek six, whereas the Magpies could only draw 1-1 away to Watford.
We say: Wolverhampton Wanderers 1-1 Newcastle United
Another 1-1 draw between the two bottom-half clubs is not beyond the realm of possibility, especially with Newcastle playing out two such stalemates of their own in the last two gameweeks.
The battle for supremacy between Traore and Saint-Maximin could make this a fascinating watch for the neutrals, and with Wolves failing to deliver on their own patch so far, we can realistically envisage a sixth 1-1 scoreline on the bounce in this fixture.
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Brighton vs. Arsenal (Saturday, 5.30pm)
Early season pace setters Brighton & Hove Albion will welcome a steadily improving Arsenal to the Amex Stadium for Saturday evening's Premier League battle.
The Seagulls salvaged a point right at the death against Crystal Palace last time out, while Mikel Arteta's men ran riot in the North London derby against Tottenham Hotspur.
We say: Brighton & Hove Albion 0-1 Arsenal
Arsenal have not always had it their own way on the South Coast, and Brighton's remarkable start to the new season means that a memorable three points against the Gunners is not beyond the realm of possibility.
However, we saw Arsenal play some of their best football under Arteta during the opening 45 of the North London derby, and if they can replicate such energy and desire at the Amex, they should have enough to grind out another hard-fought success.
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