Cremonese vs. Torino (Saturday, 5.30pm)
With renovations at Stadio Giovanni Zini now complete, Cremonese host Torino in the first home fixture of their Serie A comeback campaign.
Beaten in both of their away games so far, the hosts have endured a tough return to the top flight after 26 years away, while Il Toro have taken four points from a possible six to make a bright start to the new season.
We say: Cremonese 0-1 Torino
While Cremonese understandably lost their first two league games, in the club's seven previous Serie A seasons, they have never lost each of their first three. However, that unwanted club record could be created on Saturday evening, as Torino are a disciplined unit and can keep another clean sheet.
> Click here to read our full preview for this match
Juventus vs. Roma (Saturday, 5.30pm)
In an early clash between potential title contenders, Juventus host fellow Scudetto hopefuls Roma at the Allianz Stadium on Saturday.
The teams convene in Turin with the visitors having gathered maximum points so far, while Juve followed victory on Serie A's opening day with a dire draw last time out.
We say: Juventus 1-0 Roma
Despite their woeful recent record against them, Roma have actually won two of their three previous Serie A matches versus Juventus during August - in 2015 and 2020. Such good omens count for little, though, when the game gets under way, and Juve can grind their way to a win by a solitary goal.
> Click here to read our full preview for this match
AC Milan vs. Bologna (Saturday, 7.45pm)
After salvaging a point in their first away fixture last weekend, AC Milan return to San Siro on Saturday; hosting a Bologna side seeking their first league win.
While the champions remain unbeaten following a 1-1 draw with Atalanta, their visitors have picked up just one point from their first two Serie A matches.
We say: AC Milan 2-0 Bologna
With little to offer by way of a goal threat, Arnautovic aside, Bologna cannot afford to concede too often this season. Milan's growing depth in the final third should see them break through at some stage, and the champions should then coast home to three points.
> Click here to read our full preview for this match
Spezia vs. Sassuolo (Saturday, 7.45pm)
After taking three points from their first two games of the Serie A season, Spezia and Sassuolo meet on Saturday evening, at Stadio Alberto Picco.
Both beaten by one of Calcio's giants but winners against potential strugglers, the sides convene in Liguria, seeking maximum points before they face tougher tests next week.
We say: Spezia 1-1 Sassuolo
After a win and a loss from their opening two games, Spezia are set to draw a Serie A home game for the first time since December.
Since then, four wins and seven defeats at the picturesque Picco have underlined their inconsistency, but Luca Gotti should make them a more resilient unit; Sassuolo still lack their former firepower up front.
