Mason Mount takes the place of Hakim Ziyech, who misses out through injury, while Trevoh Chalobah comes into the team to replace Andreas Christensen after the Dane sustained a minor Achilles injury over the past 48 hours.
Tuchel suggested at his pre-match press conference that he was toying with the idea of handing a start to Reece James after a two-month absence with a hamstring injury, but the Englishman is named on the bench.
Chelsea: Mendy; Chalobah, Silva, Rudiger; Azpilicueta, Kante, Kovacic, Alonso; Mount, Havertz, Pulisic
Subs: Arrizabalaga, James, Sarr, Jorginho, Loftus-Cheek, Saul, Hudson-Odoi, Lukaku, Werner
Liverpool: Kelleher; Alexander-Arnold, Van Dijk, Matip, Robertson; Fabinho, Henderson, Thiago; Diaz, Mane, Salah
Subs: Alisson, Konate, Milner, Keita, Oxlade-Chamberlain, Minamino, Jota, Tsimikas, Origi body check tags ::