Arsenal vs. Chelsea (Sunday, 1.30pm)
From genuine Premier League title contenders to mere top-four hopefuls, Arsenal and Chelsea meet at the Emirates in an intriguing London derby on Sunday afternoon.
The Blues can move to within three points of the Gunners in the top-flight table by coming up trumps this weekend, although neither side has been pulling up trees on the attacking front.
We say: Arsenal 1-0 Chelsea
Do not expect sparks to fly at the Emirates Stadium this weekend, as Sunday's London derby pits together two sides who often enjoy plentiful possession without a killer final pass or shot to show for it.
However, with an extra couple of days of rest in their system and the crucial return of Martinelli, Arsenal have our backing to break through the Chelsea backline and use their defensive prowess to enter the international break on a high.
> Premier League preview: Arsenal vs Chelsea
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Fulham vs. Spurs (Sunday, 1.30pm)
Fresh from what could prove to be a season-saving win in the Europa League, Tottenham Hotspur's final Premier League game before the international break takes place on Sunday, an intriguing London derby away to Fulham.
Ange Postecoglou masterminded a 3-1 win over AZ Alkmaar in Thursday's European contest, while the Cottagers have had a week to reflect on a crushing 2-1 loss at the hands of Brighton & Hove Albion.
We say: Fulham 2-2 Tottenham Hotspur
Silva's 200th match as a Premier League manager should be good entertainment value for the neutrals, as Fulham can surely afford to adopt an attacking approach against Postecoglou's fatigued men.
However, the Lilywhites have shown increased levels of spirit over the past week and can likely bite back just as hard to claim a well-earned point in a second successive 2-2 top-flight stalemate.
> Premier League preview: Fulham vs Spurs
> Silva receives Traore boost: Predicted Fulham XI vs. Tottenham
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Leicester vs. Man Utd (Sunday, 7.00pm)
Leicester City boss Ruud van Nistelrooy faces his former club this weekend, as Manchester United travel to the King Power Stadium on Sunday to face the Foxes.
The two sides have already met three times this season, with United coming out on top on all three occasions.
We say: Leicester City 0-2 Manchester United
Leicester have struggled in front of goal all season, particularly in front of their own fans, and we expect that to continue this weekend.
United have already beaten the Foxes three times this season, and they should come into this match on a high after they thrashed Real Sociedad earlier in the week.
> Premier League preview: Leicester vs Man Utd
> How Leicester could line up against Man United
> How Man United could line up against Leicester
> Any fitness boosts for Amorim? Man United injury, suspension news vs. Leicester
Find out more about upcoming fixtures, odds and offers in our guide to Premier League betting sites.
