SM
| Venue: Dr. DY Patil Stadium |
FC Cincinnati | ||
| G | 18 | Roman Celentano |
| D | 2 | Alvas Powell |
| D | 15 | Yerson Mosquera |
| D | 32 | Ian Murphy |
| M | 13 | Santiago Arias |
| M | 7 | Yuya Kubo |
| M | 93 | Júnior Moreno |
| M | 31 | Álvaro Barreal |
| A | 10 | Luciano Acosta |
| A | 19 | Brandon Vazquez |
| A | 9 | Aaron-Salem Boupendza |
Columbus Crew | ||
| G | 28 | Patrick Schulte |
| D | 31 | Steven Moreira |
| D | 4 | Rudy Camacho |
| D | 18 | Malte Amundsen |
| M | 23 | Mohamed Farsi |
| M | 6 | Darlington Nagbe |
| M | 8 | Aidan Morris |
| M | 14 | Yaw Yeboah |
| A | 20 | Alexandru Mățan |
| A | 10 | Diego Rossi |
| A | 9 | Cucho Hernández |
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | FC CincinnatiCincinnati | 38 | 23 | 10 | 5 | 63 | 40 | 23 | 79 |
| 2 | Orlando City | 37 | 20 | 9 | 8 | 57 | 41 | 16 | 69 |
| 3 | Columbus Crew | 39 | 19 | 9 | 11 | 77 | 53 | 24 | 66 |
| 4 | Philadelphia UnionPhiladelphia | 37 | 17 | 10 | 10 | 61 | 43 | 18 | 61 |
| 5 | New England RevolutionNew England | 36 | 15 | 10 | 11 | 59 | 50 | 9 | 55 |
| 6 | Atlanta UnitedAtlanta | 37 | 14 | 12 | 11 | 72 | 61 | 11 | 54 |
| 7 | Nashville SCNashville | 36 | 13 | 10 | 13 | 39 | 34 | 5 | 49 |
| 8 | New York Red BullsNY Red Bulls | 37 | 12 | 11 | 14 | 42 | 45 | -3 | 47 |
| 9 | Charlotte FCCharlotte FC | 35 | 10 | 13 | 12 | 47 | 57 | -10 | 43 |
| 10 | New York City FCNY City | 34 | 9 | 14 | 11 | 35 | 39 | -4 | 41 |
| 11 | CF MontrealMontreal | 34 | 12 | 5 | 17 | 36 | 52 | -16 | 41 |
| 12 | DC United | 34 | 10 | 10 | 14 | 45 | 49 | -4 | 40 |
| 13 | Chicago Fire | 34 | 10 | 10 | 14 | 39 | 51 | -12 | 40 |
| 14 | Inter MiamiInter Miami | 34 | 9 | 7 | 18 | 41 | 54 | -13 | 34 |
| 15 | Toronto | 34 | 4 | 10 | 20 | 26 | 59 | -33 | 22 |
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Los Angeles FCLos Angeles | 37 | 17 | 10 | 10 | 61 | 41 | 20 | 61 |
| 2 | Houston DynamoHouston | 38 | 16 | 11 | 11 | 56 | 41 | 15 | 59 |
| 3 | Seattle SoundersSeattle | 38 | 16 | 11 | 11 | 45 | 36 | 9 | 59 |
| 4 | St Louis City | 36 | 17 | 5 | 14 | 64 | 51 | 13 | 56 |
| 5 | Real Salt LakeSalt Lake | 37 | 14 | 10 | 13 | 51 | 54 | -3 | 52 |
| 6 | Sporting Kansas CityKansas | 38 | 14 | 9 | 15 | 54 | 54 | 0 | 51 |
| 7 | Dallas | 37 | 12 | 13 | 12 | 44 | 41 | 3 | 49 |
| 8 | Vancouver WhitecapsVancouver | 36 | 12 | 12 | 12 | 57 | 54 | 3 | 48 |
| 9 | San Jose EarthquakesEarthquakes | 35 | 10 | 15 | 10 | 39 | 43 | -4 | 45 |
| 10 | Portland TimbersPortland | 34 | 11 | 10 | 13 | 46 | 58 | -12 | 43 |
| 11 | Minnesota UnitedMinnesota Utd | 34 | 10 | 11 | 13 | 46 | 51 | -5 | 41 |
| 12 | Austin FCAustin | 34 | 10 | 9 | 15 | 49 | 55 | -6 | 39 |
| 13 | Los Angeles GalaxyLA Galaxy | 34 | 8 | 12 | 14 | 51 | 67 | -16 | 36 |
| 14 | Colorado RapidsColorado | 34 | 5 | 12 | 17 | 26 | 54 | -28 | 27 |
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