Fiorentina vs. Como (Sunday, 11.30am)
Top-four contenders Fiorentina will aim to boost their hopes of European qualification on Sunday, as they welcome Serie A strugglers Como to Stadio Franchi.
Both sides were beaten last time out, but the Viola are pushing for a Champions League return while their visitors simply want to stay afloat.
We say: Fiorentina 2-1 Como
Only Parma have shipped more goals than Como (26) in the second half this season, while just two teams have conceded fewer after the break than Fiorentina (12).
So, even if the away side are still level during the latter stages, their high-flying hosts should be expected to come out on top.
> Serie A preview: Fiorentina vs Como
Monza vs. Lecce (Sunday, 2.00pm)
Seven weeks after his dismissal, Alessandro Nesta returns as Monza boss when the Biancorossi host Lecce in Sunday's Serie A action at the U-Power Stadium.
The two-time Champions League-winning defender was rehired this week, replacing Salvatore Bocchetti, and the cellar-dwelling hosts aim to end a four-match losing run in this weekend's gameweek 25 encounter against an opponent they have never beaten in the top flight.
We say: Monza 1-2 Lecce
Although three of the pair's five Serie A matches ended in draws, Lecce will back themselves to record a third top-flight success despite Nesta's Monza return.
Krstovic's recent form in away games and Lupi's expertise against bottom-half teams — the Salentini have accrued 22 points from 12 such games — mean Giampaolo's side could eke out a marginal success in Lombardy.
> Serie A preview: Monza vs Lecce
Udinese vs. Empoli (Sunday, 2.00pm)
Intent on securing their place in the top half of the table, Udinese will host relegation-threatened Empoli on Sunday afternoon.
The Friulani held Serie A leaders Napoli to a draw last week, while their ailing visitors lost for the fourth time in five games.
We say: Udinese 1-0 Empoli
Udinese should be full of confidence after starting the month in fine style, while injury-hit Empoli are trapped in a downward spiral.
As a result, the Friulani are set to secure maximum points, leaving their visitors ever deeper in danger.
> Serie A preview: Udinese vs Empoli
Parma vs. Roma (Sunday, 5.00pm)
Between two legs of a crucial European tie - which hangs in the balance after their midweek trip to Portugal - Roma will visit Serie A strugglers Parma on Sunday.
After the Giallorossi let victory slip from their grasp against Porto, they must now try to stay in touch with Italy's top eight.
We say: Parma 1-1 Roma
There has been only one draw between these sides across their last 15 Serie A meetings, but another could be on the cards this weekend.
Mid-table Roma may be distracted by European commitments and are rarely at their best outside the capital, while lowly Parma are scrapping for every point.
> Serie A preview: Parma vs Roma
Juventus vs. Inter Milan (Sunday, 7.45pm)
With a lot to live up to after October's eight-goal thriller, Serie A giants Juventus and Inter Milan will clash in Turin on Sunday evening.
While Juve come into the latest Derby d'Italia fresh from success in Europe, Inter are aiming to keep pace with Scudetto rivals Napoli.
We say: Juventus 1-1 Inter Milan
Following a rare flurry of goals in this fixture - eight in less than 70 minutes at San Siro - a more circumspect game should play out this weekend.
Draw specialists Juventus would surely settle for a point that will stall Inter's title charge, and their recent run of form suggests they could have turned a corner.
