Champions Manchester City welcome a faltering Tottenham to the Etihad Stadium in the headline fixture of a Sunday full of eye-catching matches around Europe.
Liverpool and Chelsea also feature amid the five Premier League games, while Barcelona host Atletico Madrid in La Liga, Napoli take on Inter Milan in Serie A, Bayer Leverkusen face Borussia Dortmund in the Bundesliga and Feyenoord entertain PSV Eindhoven in the Eredivisie.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.