Liverpool will be looking to keep their slim top-four hopes alive when they face relegation-threatened Leicester City in Monday's headline fixture.
Elsewhere, Real Betis take on Rayo Vallecano in La Liga, while Sampdoria and Empoli face each other in Serie A.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.
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| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Manchester CityMan City | 35 | 27 | 4 | 4 | 92 | 31 | 61 | 85 |
| 2 | Arsenal | 36 | 25 | 6 | 5 | 83 | 42 | 41 | 81 |
| 3 | Newcastle UnitedNewcastle | 35 | 18 | 12 | 5 | 63 | 31 | 32 | 66 |
| 4 | Manchester UnitedMan Utd | 35 | 20 | 6 | 9 | 51 | 41 | 10 | 66 |
| 5 | Liverpool | 35 | 18 | 8 | 9 | 67 | 42 | 25 | 62 |
| 6 | Brighton & Hove AlbionBrighton | 34 | 17 | 7 | 10 | 66 | 45 | 21 | 58 |
| 7 | Tottenham HotspurSpurs | 36 | 17 | 6 | 13 | 65 | 59 | 6 | 57 |
| 8 | Aston Villa | 36 | 17 | 6 | 13 | 48 | 44 | 4 | 57 |
| 9 | Brentford | 36 | 13 | 14 | 9 | 54 | 45 | 9 | 53 |
| 10 | Fulham | 36 | 15 | 6 | 15 | 52 | 49 | 3 | 51 |
| 11 | Chelsea | 35 | 11 | 10 | 14 | 36 | 41 | -5 | 43 |
| 12 | Crystal Palace | 36 | 11 | 10 | 15 | 37 | 46 | -9 | 43 |
| 13 | Wolverhampton WanderersWolves | 36 | 11 | 7 | 18 | 30 | 52 | -22 | 40 |
| 14 | Bournemouth | 36 | 11 | 6 | 19 | 37 | 69 | -32 | 39 |
| 15 | West Ham UnitedWest Ham | 36 | 10 | 7 | 19 | 38 | 52 | -14 | 37 |
| 16 | Nottingham ForestNott'm Forest | 36 | 8 | 10 | 18 | 36 | 67 | -31 | 34 |
| 17 | Everton | 36 | 7 | 11 | 18 | 32 | 56 | -24 | 32 |
| 18 | Leeds UnitedLeeds | 36 | 7 | 10 | 19 | 46 | 71 | -25 | 31 |
| 19 | Leicester CityLeicester | 35 | 8 | 6 | 21 | 49 | 64 | -15 | 30 |
| R | Southampton | 36 | 6 | 6 | 24 | 31 | 66 | -35 | 24 |
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