Porto vs. Atletico (Tuesday, 5.45pm)
Porto will be hoping to secure top spot in Group B, while Atletico Madrid will be bidding to claim third position in the section when the two teams lock horns in the Champions League on Tuesday night.
Atletico saw their last-16 hopes come to an end last week, with the La Liga outfit instead battling Bayer Leverkusen for the Europa League position in the group; Porto are currently second in the section behind Club Brugge, with one point separating the top two, who are both through to the knockout round.
We say: Porto 1-1 Atletico Madrid
A point might not be enough for Atletico to secure third spot in the group, but we are finding it difficult to back Simeone's side to win here. Porto have won their last three matches in the competition and will fancy their chances of avoiding defeat on Tuesday, with a point enough to top the section if Club Brugge lose.
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B. Leverkusen vs. Brugge (Tuesday, 5.45pm)
Bayer Leverkusen must better Atletico Madrid's result against Porto on the final Champions League matchday on Tuesday if they are to remain in Europe this season.
They will be up against Group B leaders Club Brugge, who have already secured their progression to the knockout stages for the first time in the modern era, although they need to win to ensure finishing top of Group B.
We say: Bayer Leverkusen 2-2 Club Brugge
There could be plenty of goals in Leverkusen on Tuesday, with neither side likely to be too motivated despite there still being loose ends to tie up in Group B.
Much will depend on the outcome of the other match in the group, but we can envisage a share of the spoils, which is only likely to suit one team on the night.
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Liverpool vs. Napoli (Tuesday, 8.00pm)
Liverpool must beat Napoli by three or more goals if they are to leapfrog them into top spot in Group A.
The visitors, meanwhile, are aiming to maintain their 100% record in this season's Champions League.
We say: Liverpool 2-2 Napoli
With both teams likely to rest players given the unlikelihood of this match having any real impact on their seasons, we can envisage an entertaining score draw at Anfield on Tuesday.
Liverpool will be desperate not to lose for a second successive home match, while Napoli will be determined to continue their winning streak, but they may have to settle for a point.
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> How Liverpool could line up against Napoli
Rangers vs. Ajax (Tuesday, 8.00pm)
Rangers must beat Ajax by four or more goals on Tuesday evening if they are to remain in European competition this season.
The visitors, meanwhile, were knocked out of the Champions League after suffering a 3-0 defeat at home to Liverpool last week, but they will have high hopes of dropping down to the Europa League by finishing third in Group A.
We say: Rangers 1-1 Ajax
With Ajax likely to rest a few key players given their strong position in terms of holding onto third spot in Group A, we can envisage Rangers salvaging some pride with a positive result on Tuesday.
It is incredibly unlikely to be the manner of victory they would need in order to drop down to the Europa League rather than crashing out of Europe, but it would at least ensure that they avoid ending their involvement in the Champions League without a point to their name.
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Bayern vs. Inter Milan (Tuesday, 8.00pm)
Bayern Munich and Inter Milan will round off their Champions League Group B campaigns with a clash at Allianz Arena on Tuesday evening, with the two sides set to finish first and second respectively.
The home side have won all five of their matches to sit top of the section on 15 points, while Inter have claimed 10 points to secure second, with Barcelona dropping into the Europa League from a tough group.
We say: Bayern Munich 2-1 Inter Milan
Inter will bring a four-game winning run into this match, and the Italian outfit deserve a lot of credit for their performances in Europe this season. Bayern are so difficult to back against, though, and we are expecting the German champions to put another win on the board to make it a 100% record in the group stage.
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Plzen vs. Barcelona (Tuesday, 8.00pm)
Barcelona will be bidding to end a disappointing Champions League campaign on a positive note when they make the trip to the Czech Republic on Tuesday to take on Viktoria Plzen.
The Catalan outfit have missed the chance to qualify for the last-16 stage of the competition, instead finishing third to drop into the Europa League, while Viktoria Plzen will end the group stage in fourth position.
We say: Viktoria Plzen 0-2 Barcelona
Barcelona have struggled in the group stage of this season's Champions League, but the visitors should be far too strong for their opponents here. Viktoria Plzen have conceded 20 times in their five games thus far, but we are not expecting a huge victory on Tuesday, only predicting two goals.
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> How Barcelona could line up against Viktoria Plzen
> Barcelona injury, suspension list vs. Viktoria Plzen
Sporting Lisbon vs. Frankfurt (Tuesday, 8.00pm)
A place in the last 16 is still a possibility for both Sporting Lisbon and Eintracht Frankfurt ahead of Tuesday's crunch Champions League Group D showdown at the Estadio da Luz.
Ruben Amorim's side currently occupy the second and final knockout place in the rankings, with Frankfurt in third but only behind on head-to-head points.
We say: Sporting Lisbon 2-1 Eintracht Frankfurt
Neither side should hold back on the attacking front given what is at stake this week, and Sporting have always looked a threat going forward in Europe this term - at least when they have kept all 11 men on the field.
Amorim's side have not exactly defined consistency this season and could still be caught out by a Frankfurt outfit that have had no issues finding the back of the net recently, but with the vociferous home crowd behind them, we expect the Portuguese outfit to progress as Frankfurt face a nervous wait to learn whether they will defend their Europa League crown.
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Marseille vs. Spurs (Tuesday, 8.00pm)
With everything still to play for on a tantalising final matchday in Group D, Marseille and Tottenham Hotspur do battle at the Orange Velodrome on Tuesday still vying for spots in the Champions League knockout rounds.
The Lilywhites are one point clear at the top of the section, while Les Olympiens sit in fourth place but are still capable of upsetting the apple cart and qualifying for the last 16.
We say: Marseille 2-2 Tottenham Hotspur
Facing a Tottenham side who have failed to win or score away from home in the Champions League this term spells optimism for Marseille, who simply need to go gung-ho if they are to stand any chance of keeping their Champions League dream alive.
Such an approach should yield success against a shaky Tottenham backline, but the hosts' confidence has also been shot by a poor string of results in recent weeks, and we are struggling to back either side to take all three points - instead opting for the draw that would confirm Spurs' place in the last 16.
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