Meanwhile, the hosts are without a victory in six matches, which is something that they will be wanting to end in order to start climbing up the table.
The recent form for Accrington Stanley has not been good, with the club having failed to pick up a victory in their last six matches, with their last win happening in 2021.
John Coleman will be keen to bring an end to that spell sooner than later, and Tuesday's match provides the next opportunity for that to take place if they are capable of it.
In that period the club have managed to put together four draws, showcasing their ability to fight for results no matter what, but if they can pick up some victories, there is a chance to push towards the top half of the table.
A win on Tuesday could actually take Accrington to 10th in the table depending on other results, highlighting how close things are at that point of the division.
However, they will need a much better performance than what they managed during the last meeting between these two teams, as Oxford ran away with the victory after an emphatic 5-1 result.
Goals are something that Karl Robinson's team have had no problems with this season, finding the back of the net 54 times already, and that was on full display in their most recent outing.
Oxford managed a 3-2 victory against Portsmouth where they fought back from behind and left it late to get all three points, with a 96th-minute goal from Nathan Holland securing the result.
This continued their strong run of form, with the team having gone four games in a row without a defeat, and during that time they have found the back of the net 14 times.
Throughout the season Oxford have been impressive, which is why they find themselves in the playoffs, and a victory on Tuesday could see them move into the automatic positions depending on other results.
That will provide enough motivation for them, especially since Sheffield Wednesday are just four points behind them outside of the top six, meaning the need for consistency is high.
Colby Bishop was unavailable for Accrington Stanley during their most recent outing due to an injury, and he is likely going to miss out on this match once again.
However, Seamus Conneely was able to return to the team, being fit enough to play and he should continue his time in the starting lineup as the defensive midfielder.
Robinson will also likely stick with his back three, adding five players to the midfield which is something that will help provide both defensive and offensive cover.
Accrington Stanley possible starting lineup:
Savin; Sykes, Nottingham, Rich-Baghuelo; Conneely, Butcher, Hamilton, Amankwah, Clark; Mansell, McConville
Oxford United possible starting lineup:
Stevens; McNally, Moore, Brown; Williams, Sykes, Kane, Seddon, Brannagan; Taylor, Bodin
We say: Accrington Stanley 0-3 Oxford United
Oxford United should find themselves picking up another three points at the weekend, with their recent run of form putting a lot of confidence into the squad.
In front of goal, they have caused a lot of problems lately, and that is something that should prove to be enough in order to earn them another important victory.
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