The Derby della Lanterna headlines Friday's action as Genoa and Sampdoria renew hostilities in Serie A.
There is also a Premier League showdown between Brentford and Watford, in addition to La Liga and Bundesliga matches.
Below is Sports Mole's selection of predictions and previews from today's and tomorrow's fixtures.
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| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Manchester CityMan City | 16 | 12 | 2 | 2 | 33 | 9 | 24 | 38 |
| 2 | Liverpool | 16 | 11 | 4 | 1 | 45 | 12 | 33 | 37 |
| 3 | Chelsea | 16 | 11 | 3 | 2 | 38 | 11 | 27 | 36 |
| 4 | West Ham UnitedWest Ham | 15 | 8 | 3 | 4 | 28 | 19 | 9 | 27 |
| 5 | Manchester UnitedMan Utd | 16 | 8 | 3 | 5 | 26 | 24 | 2 | 27 |
| 6 | Arsenal | 16 | 8 | 2 | 6 | 21 | 22 | -1 | 26 |
| 7 | Tottenham HotspurSpurs | 14 | 8 | 1 | 5 | 16 | 17 | -1 | 25 |
| 8 | Wolverhampton WanderersWolves | 16 | 6 | 3 | 7 | 12 | 14 | -2 | 21 |
| 9 | Brentford | 16 | 5 | 5 | 6 | 21 | 22 | -1 | 20 |
| 10 | Brighton & Hove AlbionBrighton | 15 | 4 | 8 | 3 | 14 | 16 | -2 | 20 |
| 11 | Leicester CityLeicester | 15 | 5 | 4 | 6 | 23 | 27 | -4 | 19 |
| 12 | Aston Villa | 16 | 6 | 1 | 9 | 21 | 25 | -4 | 19 |
| 13 | Everton | 15 | 5 | 3 | 7 | 19 | 25 | -6 | 18 |
| 14 | Crystal Palace | 15 | 3 | 7 | 5 | 19 | 21 | -2 | 16 |
| 15 | Leeds UnitedLeeds | 16 | 3 | 7 | 6 | 17 | 25 | -8 | 16 |
| 16 | Southampton | 16 | 3 | 7 | 6 | 14 | 24 | -10 | 16 |
| 17 | Watford | 16 | 4 | 1 | 11 | 21 | 31 | -10 | 13 |
| 18 | Burnley | 14 | 1 | 7 | 6 | 14 | 21 | -7 | 10 |
| 19 | Newcastle UnitedNewcastle | 15 | 1 | 7 | 7 | 17 | 30 | -13 | 10 |
| 20 | Norwich CityNorwich | 16 | 2 | 4 | 10 | 8 | 32 | -24 | 10 |
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | AC Milan | 17 | 12 | 3 | 2 | 36 | 19 | 17 | 39 |
| 2 | Inter Milan | 16 | 11 | 4 | 1 | 39 | 15 | 24 | 37 |
| 3 | Napoli | 16 | 11 | 3 | 2 | 34 | 12 | 22 | 36 |
| 4 | Atalanta BCAtalanta | 16 | 10 | 4 | 2 | 35 | 19 | 16 | 34 |
| 5 | Fiorentina | 17 | 10 | 0 | 7 | 31 | 22 | 9 | 30 |
| 6 | Juventus | 17 | 8 | 4 | 5 | 23 | 17 | 6 | 28 |
| 7 | Roma | 16 | 8 | 1 | 7 | 24 | 19 | 5 | 25 |
| 8 | Lazio | 16 | 7 | 4 | 5 | 32 | 30 | 2 | 25 |
| 9 | Bologna | 16 | 7 | 3 | 6 | 23 | 27 | -4 | 24 |
| 10 | Hellas VeronaHellas Verona | 16 | 6 | 5 | 5 | 32 | 28 | 4 | 23 |
| 11 | Empoli | 16 | 7 | 2 | 7 | 26 | 29 | -3 | 23 |
| 12 | SassuoloSassuolo | 16 | 5 | 5 | 6 | 26 | 25 | 1 | 20 |
| 13 | Torino | 16 | 5 | 4 | 7 | 20 | 17 | 3 | 19 |
| 14 | Sampdoria | 17 | 5 | 3 | 9 | 25 | 33 | -8 | 18 |
| 15 | Udinese | 17 | 3 | 8 | 6 | 22 | 28 | -6 | 17 |
| 16 | VeneziaVenezia | 17 | 4 | 4 | 9 | 16 | 30 | -14 | 16 |
| 17 | SpeziaSpezia | 16 | 3 | 3 | 10 | 17 | 36 | -19 | 12 |
| 18 | CagliariCagliari | 16 | 1 | 7 | 8 | 17 | 30 | -13 | 10 |
| 19 | Genoa | 17 | 1 | 7 | 9 | 18 | 34 | -16 | 10 |
| 20 | Salernitana | 17 | 2 | 2 | 13 | 11 | 37 | -26 | 8 |
