Brentford vs. Everton (Sunday, 2.00pm)
The Toffees are currently 11th in the table, collecting 15 points from their first 12 matches of the season, while Brentford are 14th, having picked up 13 points from their opening 12 games of 2021-22.
We say: Brentford 2-2 Everton
Burnley vs. Spurs (Sunday, 2.00pm)
Spurs are currently seventh in the table, four points behind fourth-placed West Ham United, while Burnley occupy 18th position, having picked up just nine points from their 12 league games in 2021-22.
We say: Burnley 1-2 Tottenham Hotspur
Leicester vs. Watford (Sunday, 2.00pm)
The Foxes have struggled to impress in the league this season, sitting down in 12th position in the table, just two points clear of 16th-placed Watford ahead of this weekend's contest between the two sides.
We say: Leicester City 1-1 Watford
Man City vs. West Ham (Sunday, 2.00pm)
Fresh from an enthralling Champions League victory over Paris Saint-Germain, Manchester City welcome fellow high-flyers West Ham United to the Etihad for Sunday's Premier League battle.
David Moyes's side also produced the goods in continental competition in midweek, seeing off Rapid Vienna with ease in the Europa League.
We say: Manchester City 2-1 West Ham United
A first-choice City backline will still have a hard time keeping out Moyes's inspired attackers on home soil, and injuries to the hosts could have the travelling contingent feeling confident about their prospects of a shock result.
The visitors' established names will certainly have the fresher legs on the pitch too and should give the champions a good run for their money, but City's goal threats in all areas of the pitch should help get them over the line.
Chelsea vs. Man Utd (Sunday, 4.30pm)
The Blues remain top of the pile with 29 points from their opening 12 games, whereas Michael Carrick's side sit seven places and 12 points below the European champions.
We say: Chelsea 2-0 Manchester United
United may possess some of the strongest attacking names the league has to offer and can boast some positive recent results against Chelsea, but Carrick's midfield and depleted defence do not inspire any confidence whatsoever.
If the Blues are capable of producing half as good a showing as they did in midweek - even with a couple more injury woes to contend with - Tuchel's table-toppers should have no problem ending their winless streak against United here.