Manchester City will be looking to make it 13 straight wins in the Premier League when they travel to St Mary's to face Southampton on January 22.
The Citizens recorded a 1-0 victory over second-placed Chelsea in the league on Saturday to stretch their advantage at the summit to 13 points.
Man City have now picked up 56 points from their opening 22 matches of the campaign and appear to be closing in on another Premier League title.
Here, Sports Mole rounds up all of the away side's injury and suspension news ahead of the showdown with Southampton, who are currently 12th in England's top flight.
Status: Out
Type of injury: International duty
Possible return date: Unknown
Riyad Mahrez is currently unavailable due to his involvement in the Africa Cup of Nations.
Status: Major doubt
Type of injury: Knock
Possible return date: January 22 (vs. Southampton)
Oleksandr Zinchenko missed out against Chelsea on Saturday due to a knock, and the Ukraine international remains a doubt for the clash with Southampton.
Status: Minor doubt
Type of injury: Fitness
Possible return date: January 22 (vs. Southampton)
Nathan Ake was absent against Chelsea on Saturday due to a lack of fitness, and the Netherlands international remains a slight doubt for the clash with Ralph Hasenhuttl's side.
MAN CITY'S SUSPENSION LIST
Possible return date: Unknown
Subject to a police charge, left-back Benjamin Mendy remains suspended by the Citizens.
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