Chelsea will be aiming to return to winning ways in the Premier League when they take on West London rivals Fulham at Stamford Bridge on Sunday.
The Blues suffered their first defeat of the season last weekend when falling to a 3-1 loss against Tottenham Hotspur, seeing them drop down to fourth place in the standings.
Thursday night brought a resounding 4-0 win over PAOK in the Europa League, however, and Maurizio Sarri now has to decide whether to leave out any of his top-flight ever-presents for this derby clash.
Doubtful: Eden Hazard (ankle), Victor Moses (back), Olivier Giroud (ankle)
Sarri made 10 changes to his starting lineup for the home clash with PAOK, retaining only goalkeeper Kepa Arrizabalaga from the Tottenham humbling.
The straightforward win provided plenty of positives, namely a goalscoring full debut for Callum Hudson-Odoi out wide and a couple of first-half strikes for Giroud.
Alvaro Morata also came off the bench to score, which should be enough to see him recalled through the middle for the visit of the Premier League's bottom-placed side, especially as Giroud is carrying a knock.
Hazard appears to have shaken off a minor ankle injury and should also be brought back into the frontline, with mass changes expected 62 hours on from the PAOK match.
Arguably the biggest call for Sarri to make is in central midfield, as N'Golo Kante's positioning was publicly questioned on the back of the Tottenham match, though the Frenchman should still get the nod here alongside pass master Jorginho and Mateo Kovacic.