Finishing eight places above their hosts last term, the visitors beat the Bavarians both home and away, so will seek to extend their dominance in this fixture.
Though it ultimately ended in bitter disappointment, by losing out to RB Leipzig in the DFB-Pokal final, a brilliant 2021-22 campaign has lifted the ambitions of a Freiburg side thriving under the management of Christian Streich.
After enjoying one of the most successful seasons in their history, the Black Forest club's first competitive fixture since that penalty shootout defeat came at Fritz-Walter-Stadion last Sunday, where they took on Kaiserslautern in the first round of the Pokal.
With their opponents still riding the crest of a wave following promotion back to the 2. Bundesliga, it took a late equaliser and extra time to see off the 1998 German champions - Roland Sallai and Ritsu Doan providing the necessary goals.
Freiburg's quest for a first-ever major trophy therefore remains alive, and they now resume league action after last term's excellent sixth-place finish.
Streich, who has been in charge at the Breisgau-based club since 2011, now has a Europa League campaign to look forward to as a result, and preparations have progressed smoothly throughout the summer.
Going unbeaten during pre-season - posting notable wins over Rennes and Rayo Vallecano in the process - demonstrates his squad's readiness to overcome the loss of defensive rock Nico Schlotterbeck to Borussia Dortmund and prosper again in the coming months.
While their opening day opponents fell just short of a top-four finish last season, Augsburg's campaign proved far more of a struggle, and they ended up only five points above the bottom three in May.
By way of response, the club's board appointed former Borussia Dortmund coach Enrico Maassen as their new head coach, replacing Markus Weinzierl, whose second spell in charge came to a conclusion earlier this summer.
Maassen previously led Dortmund's Under-23s into the 3. Liga and arrives in Bavaria with a burgeoning reputation, so will be keen to make a bright start to life in the top flight.
His competitive debut in the dugout went to plan last weekend, as Die Fuggerstadter thumped Regionalliga minnows BW Lohne 4-0 in the DFB-Pokal first round, following a mixed bag of results in pre-season.
Augsburg's hopes of a fast start to Bundesliga proceedings, though, are not aided by the fixture list throwing up first-day opposition who they have failed to defeat in their last seven attempts. Indeed, last season's losses mean that they have been beaten four times by Freiburg during that spell.
Though Augsburg are faced with a long injury list before the new Bundesliga season begins, they have secured some summer signings that can step into the breach on Saturday.
Ermedin Demirovic has joined from this week's visitors, and after making his debut in the DFB-Pokal, the Bosnian striker could join USA international Ricardo Pepi up front. The latter scored 13 MLS goals for hometown club FC Dallas in 2021, but has not managed either a goal or assist in 11 matches since moving to Germany in January.
Ruben Vargas and Reece Oxford also remain doubtful due to injury, but both could be involved at some stage; however, Lasse Gunther (thigh), Lukas Petkov (ankle), Noah Sarenren Bazee (ACL) and Tobias Strobl (knee) are all ruled out.
Christian Streich named a strong team against Kaiserslautern last week, and could field a similar starting XI in Bavaria, which would see league debuts for Matthias Ginter, Ritsu Doan and Austria striker Michael Gregoritsch.
Augsburg possible starting lineup:
Gikiewicz; Gouweleeuw, Uduokhai, Bauer; Caligiuri, Maier, Gruezo, Rexhbecaj, Iago; Pepi, Demirovic
Freiburg possible starting lineup:
Flekken; Siquet, Ginter, Lienhart, Gunter; Hofler, Eggestein; Sallai, Doan, Grifo; Gregoritsch
We say: Augsburg 1-2 Freiburg
Not known for being particularly prolific, Augsburg may need to score more than once if they are to get anything from a tough opening match against upwardly mobile opponents. Given Freiburg's recent supremacy in this fixture, too, the visitors are set to start off with a win.
For data analysis of the most likely results, scorelines and more for this match please click here.
body check tags ::
Previews by email