Premier League behemoths Manchester City and Liverpool meet for the second time in less than a week in Saturday's headline fixture, this time in the FA Cup with a place in the final at stake.
Elsewhere, top-four hopefuls Tottenham Hotspur, Manchester United and Arsenal are all in Premier League action, while Juventus and Borussia Dortmund feature across Europe and there is an Edinburgh derby in the Scottish Cup.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.