A La Liga clash between Valencia and Espanyol is one of few games taking place on New Year's Eve.
Attention elsewhere around Europe will be focusing on the calendar flipping over to 2022, including the traditional New Year's Day fixtures in England.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.
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| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Manchester CityMan City | 20 | 16 | 2 | 2 | 51 | 12 | 39 | 50 |
| 2 | Chelsea | 20 | 12 | 6 | 2 | 43 | 14 | 29 | 42 |
| 3 | Liverpool | 19 | 12 | 5 | 2 | 50 | 16 | 34 | 41 |
| 4 | Arsenal | 19 | 11 | 2 | 6 | 32 | 23 | 9 | 35 |
| 5 | West Ham UnitedWest Ham | 19 | 9 | 4 | 6 | 34 | 25 | 9 | 31 |
| 6 | Manchester UnitedMan Utd | 18 | 9 | 4 | 5 | 30 | 26 | 4 | 31 |
| 7 | Tottenham HotspurSpurs | 17 | 9 | 3 | 5 | 22 | 20 | 2 | 30 |
| 8 | Wolverhampton WanderersWolves | 18 | 7 | 4 | 7 | 13 | 14 | -1 | 25 |
| 9 | Leicester CityLeicester | 18 | 7 | 4 | 7 | 31 | 33 | -2 | 25 |
| 10 | Brighton & Hove AlbionBrighton | 18 | 5 | 9 | 4 | 17 | 18 | -1 | 24 |
| 11 | Crystal Palace | 19 | 5 | 8 | 6 | 27 | 27 | 0 | 23 |
| 12 | Aston Villa | 18 | 7 | 1 | 10 | 24 | 28 | -4 | 22 |
| 13 | Southampton | 19 | 4 | 9 | 6 | 20 | 29 | -9 | 21 |
| 14 | Brentford | 18 | 5 | 5 | 8 | 21 | 25 | -4 | 20 |
| 15 | Everton | 17 | 5 | 4 | 8 | 21 | 29 | -8 | 19 |
| 16 | Leeds UnitedLeeds | 18 | 3 | 7 | 8 | 18 | 36 | -18 | 16 |
| 17 | Watford | 17 | 4 | 1 | 12 | 22 | 35 | -13 | 13 |
| 18 | Burnley | 16 | 1 | 8 | 7 | 15 | 24 | -9 | 11 |
| 19 | Newcastle UnitedNewcastle | 19 | 1 | 8 | 10 | 19 | 42 | -23 | 11 |
| 20 | Norwich CityNorwich | 19 | 2 | 4 | 13 | 8 | 42 | -34 | 10 |
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Manchester CityMan City | 20 | 16 | 2 | 2 | 51 | 12 | 39 | 50 |
| 2 | Chelsea | 20 | 12 | 6 | 2 | 43 | 14 | 29 | 42 |
| 3 | Liverpool | 19 | 12 | 5 | 2 | 50 | 16 | 34 | 41 |
| 4 | Arsenal | 19 | 11 | 2 | 6 | 32 | 23 | 9 | 35 |
| 5 | West Ham UnitedWest Ham | 19 | 9 | 4 | 6 | 34 | 25 | 9 | 31 |
| 6 | Manchester UnitedMan Utd | 18 | 9 | 4 | 5 | 30 | 26 | 4 | 31 |
| 7 | Tottenham HotspurSpurs | 17 | 9 | 3 | 5 | 22 | 20 | 2 | 30 |
| 8 | Wolverhampton WanderersWolves | 18 | 7 | 4 | 7 | 13 | 14 | -1 | 25 |
| 9 | Leicester CityLeicester | 18 | 7 | 4 | 7 | 31 | 33 | -2 | 25 |
| 10 | Brighton & Hove AlbionBrighton | 18 | 5 | 9 | 4 | 17 | 18 | -1 | 24 |
| 11 | Crystal Palace | 19 | 5 | 8 | 6 | 27 | 27 | 0 | 23 |
| 12 | Aston Villa | 18 | 7 | 1 | 10 | 24 | 28 | -4 | 22 |
| 13 | Southampton | 19 | 4 | 9 | 6 | 20 | 29 | -9 | 21 |
| 14 | Brentford | 18 | 5 | 5 | 8 | 21 | 25 | -4 | 20 |
| 15 | Everton | 17 | 5 | 4 | 8 | 21 | 29 | -8 | 19 |
| 16 | Leeds UnitedLeeds | 18 | 3 | 7 | 8 | 18 | 36 | -18 | 16 |
| 17 | Watford | 17 | 4 | 1 | 12 | 22 | 35 | -13 | 13 |
| 18 | Burnley | 16 | 1 | 8 | 7 | 15 | 24 | -9 | 11 |
| 19 | Newcastle UnitedNewcastle | 19 | 1 | 8 | 10 | 19 | 42 | -23 | 11 |
| 20 | Norwich CityNorwich | 19 | 2 | 4 | 13 | 8 | 42 | -34 | 10 |
