The M23 derby headlines Friday night's action as Brighton & Hove Albion welcome rivals Crystal Palace to the Amex Stadium in the Premier League.
Borussia Dortmund feature in a Friday night Bundesliga game, while Sadio Mane's Senegal are among the teams resuming their Africa Cup of Nations campaigns.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.
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| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Manchester CityMan City | 22 | 18 | 2 | 2 | 54 | 13 | 41 | 56 |
| 2 | Chelsea | 22 | 12 | 7 | 3 | 45 | 17 | 28 | 43 |
| 3 | Liverpool | 20 | 12 | 6 | 2 | 52 | 18 | 34 | 42 |
| 4 | West Ham UnitedWest Ham | 21 | 11 | 4 | 6 | 39 | 27 | 12 | 37 |
| 5 | Arsenal | 20 | 11 | 2 | 7 | 33 | 25 | 8 | 35 |
| 6 | Tottenham HotspurSpurs | 18 | 10 | 3 | 5 | 23 | 20 | 3 | 33 |
| 7 | Manchester UnitedMan Utd | 20 | 9 | 5 | 6 | 32 | 29 | 3 | 32 |
| 8 | Wolverhampton WanderersWolves | 20 | 9 | 4 | 7 | 17 | 15 | 2 | 31 |
| 9 | Brighton & Hove AlbionBrighton | 20 | 6 | 10 | 4 | 21 | 21 | 0 | 28 |
| 10 | Leicester CityLeicester | 18 | 7 | 4 | 7 | 31 | 33 | -2 | 25 |
| 11 | Crystal Palace | 21 | 5 | 9 | 7 | 30 | 31 | -1 | 24 |
| 12 | Southampton | 21 | 5 | 9 | 7 | 25 | 33 | -8 | 24 |
| 13 | Aston Villa | 20 | 7 | 2 | 11 | 27 | 32 | -5 | 23 |
| 14 | Brentford | 20 | 6 | 5 | 9 | 24 | 30 | -6 | 23 |
| 15 | Everton | 19 | 5 | 4 | 10 | 24 | 34 | -10 | 19 |
| 16 | Leeds UnitedLeeds | 19 | 4 | 7 | 8 | 21 | 37 | -16 | 19 |
| 17 | Watford | 19 | 4 | 2 | 13 | 23 | 37 | -14 | 14 |
| 18 | Norwich CityNorwich | 21 | 3 | 4 | 14 | 10 | 45 | -35 | 13 |
| 19 | Newcastle UnitedNewcastle | 20 | 1 | 9 | 10 | 20 | 43 | -23 | 12 |
| 20 | Burnley | 17 | 1 | 8 | 8 | 16 | 27 | -11 | 11 |
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Wycombe WanderersWycombe | 27 | 15 | 7 | 5 | 44 | 30 | 14 | 52 |
| 2 | Sunderland | 27 | 15 | 6 | 6 | 52 | 33 | 19 | 51 |
| 3 | Rotherham UnitedRotherham | 25 | 15 | 5 | 5 | 45 | 18 | 27 | 50 |
| 4 | Wigan AthleticWigan | 22 | 15 | 3 | 4 | 42 | 21 | 21 | 48 |
| 5 | MK Dons | 26 | 13 | 7 | 6 | 46 | 31 | 15 | 46 |
| 6 | Oxford UnitedOxford Utd | 26 | 12 | 7 | 7 | 40 | 29 | 11 | 43 |
| 7 | Plymouth ArgylePlymouth | 25 | 12 | 7 | 6 | 40 | 29 | 11 | 43 |
| 8 | Sheffield WednesdaySheff Weds | 25 | 10 | 10 | 5 | 34 | 29 | 5 | 40 |
| 9 | Portsmouth | 24 | 10 | 7 | 7 | 29 | 24 | 5 | 37 |
| 10 | Accrington StanleyAccrington | 26 | 10 | 6 | 10 | 32 | 41 | -9 | 36 |
| 11 | Ipswich TownIpswich | 26 | 9 | 8 | 9 | 43 | 36 | 7 | 35 |
| 12 | Burton Albion | 25 | 10 | 5 | 10 | 32 | 31 | 1 | 35 |
| 13 | Cheltenham TownCheltenham | 26 | 7 | 10 | 9 | 32 | 45 | -13 | 31 |
| 14 | Charlton AthleticCharlton | 26 | 8 | 6 | 12 | 32 | 32 | 0 | 30 |
| 15 | Shrewsbury TownShrewsbury | 26 | 8 | 6 | 12 | 26 | 29 | -3 | 30 |
| 16 | Cambridge UnitedCambridge | 25 | 7 | 9 | 9 | 33 | 38 | -5 | 30 |
| 17 | Bolton WanderersBolton | 25 | 8 | 5 | 12 | 32 | 37 | -5 | 29 |
| 18 | Lincoln CityLincoln | 25 | 7 | 7 | 11 | 29 | 33 | -4 | 28 |
| 19 | Fleetwood TownFleetwood | 25 | 7 | 7 | 11 | 38 | 43 | -5 | 28 |
| 20 | AFC Wimbledon | 23 | 6 | 8 | 9 | 30 | 36 | -6 | 26 |
| 21 | Morecambe | 25 | 6 | 6 | 13 | 34 | 49 | -15 | 24 |
| 22 | Crewe AlexandraCrewe | 26 | 5 | 7 | 14 | 24 | 44 | -20 | 22 |
| 23 | Gillingham | 25 | 3 | 9 | 13 | 19 | 41 | -22 | 18 |
| 24 | Doncaster RoversDoncaster | 25 | 4 | 4 | 17 | 17 | 46 | -29 | 16 |
