The England captain finally made the net ripple in the Premier League at the weekend against Newcastle United, but Spurs were made to work for their 3-2 success at St James' Park.
Here, Sports Mole rounds up all of Tottenham's latest injury and suspension news ahead of the contest.
Type of injury: Hamstring
Possible return date: Unknown
Ryan Sessegnon continues to battle his way back from a hamstring problem, and Santo revealed before the Newcastle win that the ex-Fulham man was not yet training with the group, making a comeback here incredibly unlikely.
Status: Major doubt
Type of injury: Knock
Possible return date: October 21 (vs. Vitesse)
Matt Doherty did not take part in Saturday's game after picking up a knock during the international break, and the right-back remains doubtful for this contest.
TOTTENHAM'S SUSPENSION LIST
Spurs have no players suspended for this match.