Torino vs. Cagliari (Sunday, 11.35am)
Having held city rivals Juventus to a draw last time out, the Granata will now face a side that have lost only once since the start of the year.
We say: Torino 1-0 Cagliari
Torino may have tailed off in recent weeks, but will be emboldened by taking a point from perhaps their biggest game of the season, and are now ready to get back on the winning trail.
Several months plagued by injury and lack of match-sharpness has held Andrea Belotti back this term, but his crucial goal at Juve could trigger a more productive patch from the Italy striker - and Cagliari may be among those made to pay.
Hellas Verona vs. Venezia (Sunday, 2.05pm)
This week's visitors blew a three-goal lead to lose December's reverse fixture 4-3, so not only have three precious points in their sights but also hope of exacting revenge.
We say: Hellas Verona 2-1 Venezia
Hellas will do the double over their neighbours from the lagoon, as their goal threat is just too much for Venezia to handle.
Though a European place will most probably elude them, the hosts are back on an upward trajectory, and they can push forward freely on Sunday due to their visitors' failings in the final third.
Spezia vs. Roma (Sunday, 5.05pm)
The teams meet on Sunday evening, with Jose Mourinho under pressure to produce a first victory of the month against a side managed by one of his former players.
We say: Spezia 1-2 Roma
It will surely not be a straightforward process - as only Empoli have conceded more goals than Roma's 13 in Serie A during 2022 - but the visitors can return to the capital with all three points.
Having lost consecutive games and starting without their first-choice striker, Spezia's downward trend will continue - with Juventus also on the horizon next week.
Lazio vs. Napoli (Sunday, 7.50pm)
While the hosts - who were knocked out of the Europa League by Porto - have gone unbeaten in six domestic fixtures, their visitors are without a win in four games following a 4-2 defeat to Barcelona.
We say: Lazio 2-2 Napoli
The influence of 'Sarri-ball' lives on, as both sides favour an attractive, possession based style which should make this clash of two southern rivals a pleasure to watch.