Ryan Sessegnon will again be unavailable for selection due to a long-term hamstring problem, while Bryan Gil is likely to miss out with the thigh issue that he picked up against Burnley in the EFL Cup on Wednesday.
Spurs otherwise have a fully-fit squad, and there are not expected to be many surprises when it comes to team selection from head coach Nuno Espirito Santo.
Nuno has decisions to make in the middle of his defence, but the fact that Eric Dier was an unused substitute against Burnley suggests that he will come back into the side this weekend.
Sergio Reguilon will also be back in the starting XI at left-back, but Dele Alli and Harry Winks could again both be left out of the squad, with the duo fighting to save their careers at the Tottenham Hotspur Stadium.
Tottenham Hotspur possible starting lineup: Lloris; Emerson, Romero, Dier, Reguilon; Skipp, Hojbjerg; Lucas, Ndombele, Son; Kane
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