Dynamo Kiev vs. Bayern (Tuesday, 5.45pm)
Julian Nagelsmann's side have taken 12 points from 12 to sit at the top of the rankings, whereas the Ukrainian hosts are last with just one point to their name.
We say: Dynamo Kiev 0-2 Bayern Munich
Dynamo will hope to experience some long-awaited joy in front of goal against a depleted Bayern defence, but their lack of firepower in Europe is set to cost them dear.
Nagelsmann will not accept a hint of complacency from his side as they endeavour to seal top spot in the group, so we can only back a near full-strength Bayern to get the job done.
Villarreal vs. Man Utd (Tuesday, 5.45pm)
Man United know that a win against the Yellow Submarine will confirm their spot in the knockout round of the competition with a game to spare, but a defeat would leave them vulnerable in Group F.
We say: Villarreal 1-1 Manchester United
It will be fascinating to see what type of reaction there is from Man United, who were so poor at Watford on Saturday. A draw would be a decent result for the Red Devils considering that they finish their campaign at home to Young Boys, and we can see the two teams playing out a low-scoring draw here.
Barcelona vs. Benfica (Tuesday, 8.00pm)
The Catalan powerhouses will hope that lightning does not strike twice against Jorge Jesus's side, who sunk Barca 3-0 when the sides met earlier in Group E.
We say: Barcelona 2-1 Benfica
Barcelona boss Xavi is certainly working with a more solid rearguard for this encounter, and the injection of confidence received from assuring themselves of a top-two spot will be invaluable.
Benfica will not be broken down lightly and have fond memories of their September battle with Barca, but we still expect Xavi's reign to continue in perfect fashion here.
Young Boys vs. Atalanta (Tuesday, 8.00pm)
Fourth will welcome third in Group F on Tuesday night, with Young Boys and Atalanta BC both battling to keep their Champions League knockout-round hopes alive.
Young Boys are currently bottom of the section with just three points to show from their opening four matches, while Atalanta occupy third, two points behind second-placed Villarreal and leaders Manchester United.
We say: Young Boys 1-2 Atalanta BC
Atalanta's away form this season has been impressive, and we are backing the Italian outfit to pick up a huge three points at the expense of Young Boys, who will be missing a number of key players through injury.
Sevilla vs. Wolfsburg (Tuesday, 8.00pm)
The hosts are bottom of the rankings with just three points to their name, while their German counterparts occupy the Europa League spot with two games remaining.
We say: Sevilla 0-1 Wolfsburg
The absence of hotshot En-Nesyri could prove fatal against a Wolfsburg side already appearing more well-drilled under Kohfeldt, and it has just not gone Sevilla's way in Europe this term.
The visitors demonstrated their fighting spirit against Arminia and will be boosted by the return of the highly-rated Lacroix, so we expect Wolfsburg to break into the top two with a hard-fought win in Seville.
Lille vs. Salzburg (Tuesday, 8.00pm)
Jocelyn Gourvennec's side prevailed 2-1 against Sevilla on matchday four, while Salzburg went down by the same scoreline to Wolfsburg.
We say: Lille 1-1 Red Bull Salzburg
Lille's depleted defence and midfield will have a hard time keeping out Salzburg's bright young attackers, but the visitors have struggled for consistency in recent weeks.
With Group G surely set to go right down to the wire either way, we expect a share of the spoils at the Stade Pierre-Mauroy, with Gourvennec's hopes of victory dashed by a concerning number of regular starters absent.
Chelsea vs. Juventus (Tuesday, 8.00pm)
While the Old Lady triumphed in Turin when the clubs last met - before going on to seal progress to the last 16 with four wins from four - the reigning champions are just a point away from confirming their place in the knockout stages.
We say: Chelsea 1-0 Juventus
Chelsea can gain a measure of revenge for their defeat in Italy earlier this season by ending Juve's flawless record and ensuring the race for top spot goes down to the final matchday in Group H.
Though the visitors can be flaky against some of the more modest sides they encounter, they rarely concede many in big games, so will be edged out by the odd goal at Stamford Bridge due to their hosts' wealth of attacking options.
Malmo vs. Zenit (Tuesday, 8.00pm)
Though both sides are effectively out of the running to progress from Champions League Group H, the chance to stay in continental competition is on the line when Malmo meet Zenit St Petersburg on Tuesday.
Still pointless after a chastening first four games, the hosts must win to stay in contention for a Europa League spot, while their fellow national champions can secure third place with a point.
We say: Malmo 1-2 Zenit St Petersburg
Malmo will surely get off the mark in terms of goals on Tuesday night, but their visitors' attacking potential can cause them more problems after a dominant display when the teams met in September.
For that reason, the Swedish champions will go down to a fifth consecutive defeat; sending Zenit through to the Europa League knockout rounds as a result.