Liverpool manager Jurgen Klopp has made a total of nine changes for Tuesday's Premier League clash with Southampton at St Mary's.
Alisson Becker and Ibrahima Konate are the only two players to hold their spots from the FA Cup final, with Klopp making significant alterations after 120 minutes and penalties at Wembley.
Virgil van Dijk is given the night off as Joel Matip starts in defence, while Joe Gomez and Kostas Tsimikas displace Andy Robertson and Trent Alexander-Arnold.
Jordan Henderson and Thiago Alcantara are considered fit enough for spots on the bench, but Fabinho again misses out owing to his hamstring injury.
Curtis Jones and James Milner are both recalled to the engine room, while Harvey Elliott makes a first Premier League start since his horrific ankle injury at Leeds United in September.
Diogo Jota and Roberto Firmino are joined in the attack by Takumi Minamino, while Mohamed Salah and Sadio Mane are also rested by Klopp.
Liverpool starting lineup: Alisson; Gomez, Matip, Konate, Tsimikas; Milner, Elliott, Jones; Minamino, Firmino, Jota
Subs: Kelleher, Williams, Robertson, Oxlade-Chamberlain, Keita, Thiago, Henderson, Diaz, Origi
Southampton starting lineup: McCarthy; Walker-Peters, Lyanco, Stephens, Salisu; Redmond, Diallo, Ward-Prowse, Elyounoussi; Tella, Broja
Subs: Caballero, Bednarek, Valery, Romeu, Djenepo, S. Armstrong, A. Armstrong, Adams, Long body check tags ::
