The Reds have taken six points from their first two fixtures with Porto and AC Milan, thrashing the former 5-1 after another goal-laden performance saw them sink the Rossoneri 3-2 at Anfield.
Liverpool and Atletico are no strangers to one another - having met multiple times in European competition down the years - but the Reds have posted a mixed bag of results against their Spanish counterparts.
Here, Sports Mole takes a closer look at Liverpool's previous meetings with the La Liga champions.
Liverpool's maiden meeting with Atletico Madrid came in the 2008-09 Champions League campaign at the Vicente Calderon, where Robbie Keane would break the deadlock befoe Simao's equaliser rescued a point for the Spaniards in a 1-1 stalemate.
The two sides would shake hands on another two-goal draw at Anfield only two weeks later, as Maxi Rodriguez - who would transfer to Liverpool just over a year later - opened the scoring before a Steven Gerrard penalty in the third minute of second-half injury time saw Liverpool claim a point.
Liverpool and Atletico would take the top two spots in Group D that year before being knocked out in the quarter-finals and last-16 stage respectively, but they would reconvene just one year later in the semi-finals of the Europa League.
Diego Forlan's strike handed Atletico a 1-0 advantage in Madrid in the first leg, and while Liverpool marched to a 2-1 second-leg win after extra time courtesy of Alberto Aquilani and Yossi Benayoun's strikes, Forlan would haunt the Reds with the deciding away goal.
The two sets of fans would have to wait nearly 10 years before their sides renewed hostilities once more in the last-16 of the 2019-20 Champions League, with Liverpool seeking to defend their crown from the 2019 final.
The first leg at the Wanda Metropolitano began in miserable fashion for Liverpool as Saul Niguez took all of four minutes to open the scoring, but there were no more goals to be had as the Reds sought to overturn a 1-0 deficit on home soil.
Georginio Wijnaldum's header would force extra time and Roberto Firmino would proceed to put the Reds 2-0 to the good, but in one of the most memorable nights in Anfield history for all the wrong reasons for Liverpool, substitutes Marcos Llorente and Alvaro Morata combined for three quickfire goals to end the Reds' European defence.
As a result, Liverpool's inconsequential Europa League win represents their only success from six previous meetings with Atletico, and Jurgen Klopp will endeavour to break the Reds' Champions League hoodoo versus Diego Simeone's side on Tuesday night. body check tags ::