Moldova vs. Scotland (Friday, 5.00pm)
Scotland can secure a World Cup 2022 qualifying playoff spot by overcoming minnows Moldova at Stadionul Zimbru in Chisinau on Friday evening.
Steve Clarke's men have won four games in a row in Group F, but any sort of slip up against bottom side Moldova will give Israel the chance to pounce.
We say: Moldova 0-4 Scotland
Scotland almost pride themselves on never being able to achieve things the easy way, but this should - should - be a routine away win for Clarke's side.
Moldova have lost their last seven qualifiers by an aggregate score of 23-3, whereas Scotland have won four in a row 6-2 combined, so we are going for a big-scoring away win here.
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Italy vs. Switzerland (Friday, 7.45pm)
The top two teams in Group C will lock horns for a crucial battle on Friday night, as Italy welcome Switzerland in their penultimate World Cup 2022 qualification fixture.
Both sides are assured of at least making the playoffs, but first position is still open for discussion, with the pair collecting 14 points from their six matches in the section thus far.
We say: Italy 2-1 Switzerland
Switzerland are more than capable of picking up a positive result on Friday, but the visitors will be missing some huge players for this match. We are expecting this to be a tight match between two strong sides but believe that Italy will just have enough to pick up a vital three points on home soil.
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> How Italy could line up against Switzerland
N. Ireland vs. Lithuania (Friday, 7.45pm)
The bottom two teams in Group C will lock horns on Friday night, as Northern Ireland welcome Lithuania to Windsor Park for their penultimate World Cup 2022 qualification match.
Northern Ireland are currently fourth in the section, having picked up five points from their six matches thus far, while Lithuania are bottom with three points to show from their seven qualification games.
We say: Northern Ireland 1-0 Lithuania
Northern Ireland put four past Lithuania in their last meeting, but we are expecting a much tighter contest here. It would not be a surprise to see the two sides play out a draw, but we believe that Northern Ireland's superior quality will shine through to allow them to collect all thee points at Windsor Park.
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Austria vs. Israel (Friday, 7.45pm)
Israel's World Cup 2022 qualifying hopes are hanging by a thread as they prepare to take on Austria at Worthersee Stadion in Klagenfurt on Friday evening.
The Blue and Whites are third in Group F, four points behind second-place Scotland with two games to go, while Austria are three points worse off in fourth.
We say: Austria 1-1 Israel
Scotland's match with Moldova concludes shortly ahead of kickoff in Klagenfurt, so Israel will know whether they have a shot of finishing in the top two before a ball is kicked.
Austria are themselves left waiting on other results to gain backdoor entry to the playoffs, and we can see the sides playing out an uneventful draw in this Group F showdown.
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Denmark vs. Faroe Islands (Friday, 7.45pm)
Denmark will be looking to extend their perfect record in World Cup 2022 qualifying when they take on the Faroe Islands at Parken Stadion in Copenhagen on Friday evening.
The Danes have already booked their place in next year's tournament with two games to spare, while the Faroe Islands are battling with Moldova to avoid bottom place in Group F.
We say: Denmark 3-0 Faroe Islands
Denmark have already booked their place at the next World Cup, but the Red and Whites will be eager to keep their momentum going into 2022.
The Faroe Islands have looked far tougher to beat in their last four games, a run that includes a win over Moldova, but we cannot see past a routine home victory on Friday.
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Andorra vs. Poland (Friday, 7.45pm)
Poland will seek to keep the pressure on England in World Cup 2022 Qualifying Group I when they travel to Andorra on Friday night.
The visitors sit three points behind the Three Lions in second place, while Andorra's expected elimination has already been confirmed.
We say: Andorra 0-4 Poland
With Poland boss Sousa potentially tempted to field his strongest XI here and guarantee a top-two finish before the final matchday, we can only envisage one outcome.
The visitors have found form at a crucial time in World Cup Qualifying, while Andorra's campaign cannot end quickly enough, so Sousa's men should march to all three points with plenty of goals en route.
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England vs. Albania (Friday, 7.45pm)
With World Cup 2022 qualification yet to be assured, England kick off their November fixtures with the visit of Albania to Wembley on Friday.
Gareth Southgate's men currently hold a three-point lead atop the rankings, while their visitors are still in with a shot of a top-two finish as they occupy third place.
We say: England 2-0 Albania
Reja and Albania command plenty of respect for the way they have conducted themselves in World Cup Qualifying, and the visitors will still be daring to dream as they step foot onto the Wembley turf.
England are under pressure to respond following their disappointing showing against Hungary, but their record in this fixture speaks for itself, and Southgate's side should take a giant leap towards qualification with all three points here.
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> How England could line up against Albania
Hungary vs. San Marino (Friday, 7.45pm)
With their hopes of World Cup 2022 qualification hanging by the thinnest of threads, Hungary prepare to welcome minnows San Marino to the Puskas Arena on Friday night.
The hosts' destiny is out of their own hands ahead of the final two Qualifying games, while San Marino are simply trying to restore a sense of pride after another doomed campaign.
We say: Hungary 4-0 San Marino
The result of this game may end up paling into insignificance for both sides depending on results elsewhere, but no surprises should be sprung in Budapest.
Hungary were not entirely convincing in their previous success over San Marino, but a much-changed XI should still have enough to put the minnows to the sword.
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Bosnia H'vina vs. Finland (Saturday, 2.00pm)
Bosnia-Herzegovina and Finland will both aim to move above Ukraine into second place in World Cup 2022 Qualifying Group D during Saturday's battle at the Bilino Polje Stadium.
The hosts occupy fourth spot in the group with seven points taken from six games so far, while Markku Kanerva's side are one point and one place better off than their opponents.
We say: Bosnia-Herzegovina 2-2 Finland
Another entertaining affair should be in store this weekend, with both sides desperate to gain the upper hand in the battle for second place before the final matchday.
Finland may have a greater sense of urgency to prevail given that they will face France on the final day, but Bosnia will not go down without a fight, and we expect the draw specialists to take yet another point from this encounter.
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Norway vs. Latvia (Saturday, 5.00pm)
Norway will enter Saturday's World Cup 2022 qualification fixture against Latvia knowing that a victory would, temporarily at least, move them to the top of Group G.
The home side are currently second in the section, two points behind leaders Netherlands, while Latvia are fifth, having picked up just five points from their eight matches thus far.
We say: Norway 2-0 Latvia
The absence of Haaland is a huge blow for Norway, but the home side still have plenty of quality in the forward positions, and we are expecting them to pick up another important victory in relatively routine fashion here.
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France vs. Kazakhstan (Saturday, 7.45pm)
Reigning world champions France will aim to assure themselves of a spot in Qatar when they welcome Kazakhstan to the Parc des Princes for Saturday's World Cup 2022 Qualifying battle.
Didier Deschamps's side will assure themselves of a first-placed finish with all three points this weekend, while their visitors have already been consigned to a fifth-placed standing.
We say: France 3-0 Kazakhstan
France will be forced to deal with the absences of some key players this month, but the chance to guarantee a first-placed finish with a game to spare is all the motivation that the hosts need to get the job done.
Kazakhstan have very little to play for and can therefore play without fear at the Parc des Princes, but Les Bleus ought to book their place in Qatar with a professional performance.
> Click here to read our full preview for this match
> How France could line up against Kazakhstan
Belgium vs. Estonia (Saturday, 7.45pm)
Belgium can officially book their place at World Cup 2022 with victory over Estonia in Saturday's qualifier at the King Baudouin Stadium in Brussels.
The Red Devils are five points clear at the top of Group E with two rounds of games to play, while Estonia can finish no higher than their current standing of fourth place.
We say: Belgium 3-0 Estonia
Belgium have lost their last two matches and will now be after six points from six to conclude their World Cup qualifying campaign.
Martinez will likely rotate his injury-hit squad, but even so there is far too much quality in the Red Devils' ranks to be given a scare by Estonia.
