Netherlands goalkeeper Jasper Cillessen will play no part in Tuesday evening's friendly against England at Wembley.
The Ajax stopper has been ruled out with a broken nose that he sustained during a training ground collision with teammate Klaas Jan Huntelaar.
As a result, Cillessen has become the second player to withdraw from the Dutch squad along with playmaker Wesley Sneijder, who has a muscular injury.
Centre-back Daley Blind has also picked up a hamstring problem, but there have been suggestions that he will be passed fit to feature in London.
In the absence of Cillessen, either Kenneth Vermeer or Jeroen Zoet will keep goal for the Dutch.
