Corinthians vs. Juventude (Saturday, 8.30pm)
Sitting inside the bottom four, Juventude have endured a torrid start to the campaign, with a result against Corinthians this weekend a target for O Azul.
We say: Corinthians 3-0 Juventude
While not without faults this season, Corinthians have enjoyed the best start of any Serie A side in Brazil.
Expect Corinthians to bounce back from recent defeat with a comfortable home victory over Juventude this weekend.
Atletico Mineiro vs. Santos (Saturday, 11.00pm)
Scratching around in mid-table, Santos will be looking to use Saturday's clash as a chance to kick-start their campaign.
We say: Atletico Mineiro 2-0 Santos
Santos must find an improvement in form and quickly if they wish to challenge higher up the table this season.
Unlikely to threaten Mineiro's chances of a victory this weekend, expect the hosts to take a straightforward victory on Saturday.
Fluminense vs. Atletico GO (Saturday, 11.00pm)
Slumped inside the bottom four, Goianiense face a tough test against a Fluminense side targeting continental football.
We say: Fluminense 2-0 Atletico Goianiense
Two sides in contrasting form, Fluminense will expect to take advantage of relegation-threatened Goianiense.
Expect a comfortable home victory for Fluminense, as Goianiense's difficult start to the season to continue on Saturday.
Cuiaba vs. Bragantino (Saturday, 11.00pm)
They currently reside in the Brasileiro relegation zone, while Bragantino enter the weekend in 11th place.
We say: Cuiaba 1-0 Bragantino
Although Cuiaba enter the contest in the relegation zone, they have emerged victorious from the last two home meetings with Bragantino, and we think they will manage to edge out the visitors on Saturday.
Internacional vs. Flamengo (Sunday, 1.00am)
The visitors, meanwhile, will be hoping to avoid a third consecutive defeat after losing to Fortaleza and Bragantino in their last two outings.
We say: Internacional 1-1 Flamengo
Although Flamengo are currently in 14th place, fourth consecutive top two Brasileiro finishes suggests that it is only a matter of time before they start moving up the table, and we think the visitors hold their hosts to a point on Saturday, which would give Internacional their fourth consecutive home league draw.