The Blues are currently second in the section, having picked up nine points from their four matches, while Juventus sit at the summit, three points clear of their opponents here.
Thomas Tuchel's side will enter the key European fixture off the back of an impressive 3-0 victory at Leicester City in the Premier League on Saturday afternoon.
Here, Sports Mole rounds up all of Chelsea's latest injury and suspension news ahead of the contest.
Status: Major doubt
Type of injury: Ankle
Possible return date: November 23 (Juventus)
Romelu Lukaku has made excellent progress in his recovery from an ankle injury and is in contention to feature against Juventus in London on Tuesday night.
Type of injury: Hamstring
Possible return date: Unknown
Mateo Kovacic suffered a hamstring problem in a training session last month, and a date for the Croatia international's return to action has not yet been set.
CHELSEA'S SUSPENSION LIST
Chelsea have no players suspended for this match.