Barcelona's first match since the end of August will see them take on Bayern Munich in the group stage of the Champions League on Tuesday evening.
The Catalan giants had initially been due to face Sevilla in La Liga on Saturday, but the match was postponed due to a clash with World Cup qualifiers in South America.
Ronald Koeman's side, who were knocked out in the last-16 stage of last season's European Cup, will be looking to get their Group E challenge off to the perfect start against the German giants.
Here, Sports Mole rounds up all of Barcelona's injury and suspension news ahead of their European opener on home soil.
Status: Out
Type of injury: Calf
Possible return date: Unknown
Barcelona will be without the services of new signing Aguero once again due to a calf problem, and the Argentine is not expected to be available for selection until at least the end of October.
Status: Out
Type of injury: Knee
Possible return date: Unknown
Dembele was forced to undergo knee surgery due to the injury that he picked up while representing France at Euro 2020, and the attacker will be on the sidelines until the latter stages of the year.
Status: Out
Type of injury: Knee
Possible return date: Unknown
Fati has returned to light training for Barcelona after a serious knee injury, but the Spain international will not be available for this contest, and it is unclear when he might be cleared to make his first-team return.
Status: Major doubt
Type of injury: Knock
Possible return date: September 14 (vs. Bayern)
Sergino Dest returned from international duty with a knock, and the American has therefore emerged as a doubt for Tuesday's European contest with Bayern.
Status: Out
Type of injury: Knee
Possible return date: Unknown
Martin Braithwaite could allegedly be out for up to four months due to the knee problem that he suffered against Getafe before the international break, and the club are thought to be considering surgery.
BARCELONA'S SUSPENSION LIST
Barcelona have no players suspended for this match.
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