Norwich vs. Arsenal (Sunday, 3.00pm)
Having cruised to their 10th top-flight victory last time out at Leeds, and then serenely progressed to the EFL Cup semi-finals, the Gunners now meet a home side who have won just twice all season.
We say: Norwich City 1-3 Arsenal
Momentum is certainly in Arsenal's favour heading towards the end of a largely disappointing year, and they are set to extend their winning streak to five with another success on Boxing Day.
Remarkably, Norwich have never taken three Premier League points on December 26, and a thin squad disrupted by illness and injuries cannot hope to compete with their capital counterparts this time around.
Spurs vs. Crystal Palace (Sunday, 3.00pm)
While the home side currently occupy seventh position in the standings, Palace are down in 11th spot after just one win from their last six fixtures.
We say: Tottenham Hotspur 2-0 Crystal Palace
Having named a strong team in midweek, Conte is valuing momentum over squad momentum, and we feel that will continue on Boxing Day. While Palace will pose a threat to their hosts on the break, Spurs should have enough in the tank to collect all three points.
Man City vs. Leicester (Sunday, 3.00pm)
While the champions are now favourites to defend their crown after a scintillating streak since early November, their inconsistent visitors arrive at the Etihad Stadium having dramatically lost out in the EFL Cup quarter-finals.
We say: Manchester City 2-0 Leicester City
After putting seven past Leeds and netting four versus Newcastle, there is no reason to expect City to slow down heading in to 2022, and the home side can pick up three points against hit-and-miss opponents even if they are not at their free-flowing best.
Leicester's troubles will go on, as even a vast improvement in James Maddison's performances of late cannot help them match a multi-talented side on top form - particularly given their defensive difficulties.
West Ham vs. Southampton (Sunday, 3.00pm)
Meanwhile, the Saints are without success in their last six top-flight fixtures, leaving the visitors down in 15th position ahead of the trip to the London Stadium.
We say: West Ham United 2-1 Southampton
Despite the difference in league positions, everything points to this being a close game. Southampton will fancy their chances of causing West Ham problems in the final third, but we are backing the Hammers to battle their way to a hard-fought win.
Aston Villa vs. Chelsea (Sunday, 5.30pm)
Meanwhile, Villa return to action sitting in 10th position, a consequence of recording 12 points from six matches since Steven Gerrard's arrival.
We say: Aston Villa 1-1 Chelsea
With so many uncertainties over squad selection, this is a difficult match to call. Nevertheless, we cannot ignore Villa's improvement under Gerrard and Chelsea's potential tiredness, leading to us predicting a low-scoring draw.
Brighton vs. Brentford (Sunday, 8.00pm)
Meanwhile, Brentford have collected two victories from their last four outings, leaving the Bees level on points with their hosts in the Premier League standings.
We say: Brighton & Hove Albion 1-1 Brentford
Having established a considerable gap between themselves and the bottom three, there is a certain degree of freedom for both teams to push for all three points. Nevertheless, we can only see a low-scoring share of the spoils, a result which would take both teams one small step closer to survival.